[Federal Register Volume 74, Number 216 (Tuesday, November 10, 2009)]
[Notices]
[Page 58015]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: E9-27051]


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ENVIRONMENTAL PROTECTION AGENCY

[FRL-8978-7; Docket ID No. EPA-HQ-ORD-2009-0245]


Draft Toxicological Review of Hydrogen Cyanide and Cyanide Salts: 
In Support of the Summary Information on the Integrated Risk 
Information System (IRIS)

AGENCY: Environmental Protection Agency (EPA).

ACTION: Notice of peer-review workshop.

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SUMMARY: EPA is announcing that Versar, Inc., an EPA contractor for 
external scientific peer review, will convene an independent panel of 
experts and organize and conduct an external peer-review workshop to 
review the external review draft document titled, ``Toxicological 
Review of Hydrogen Cyanide and Cyanide Salts: In Support of Summary 
Information on the Integrated Risk Information System (IRIS)'' (EPA/
635/R-08/016). The draft document was prepared by the National Center 
for Environmental Assessment (NCEA) within EPA's Office of Research and 
Development. EPA previously announced the 60-day public comment period 
(ending November 23, 2009) for the draft document in the Federal 
Register on September 23, 2009 (74 FR 48539). EPA will consider public 
comments and recommendations from the expert panel workshop as EPA 
finalizes the draft document.
    The public comment period and the external peer-review workshop are 
separate processes that provide opportunities for all interested 
parties to comment on the document. EPA intends to forward public 
comments submitted in accordance with the September 23, 2009, Federal 
Register notice (74 FR 48539) to Versar, Inc., for consideration by the 
external peer-review panel prior to the workshop.
    EPA is releasing this draft document solely for the purpose of pre-
dissemination peer review under applicable information quality 
guidelines. This document has not been formally disseminated by EPA. It 
does not represent and should not be construed to represent any Agency 
policy or determination.
    Versar, Inc. invites the public to register to attend this workshop 
as observers. In addition, Versar, Inc. invites the public to give oral 
and/or provide written comments at the workshop regarding the draft 
document under review. Space is limited, and reservations will be 
accepted on a first-come, first-served basis. The draft document and 
EPA's peer-review charge are available primarily via the Internet on 
NCEA's home page under the Recent Additions and Publications menus at 
http://www.epa.gov/ncea. In preparing a final report, EPA will consider 
Versar Inc.'s report of the comments and recommendations from the 
external peer-review workshop and any public comments that EPA 
receives.

DATES: The peer-review panel workshop will begin on December 14, 2009, 
at 9 a.m. and end at 5 p.m.

ADDRESSES: The peer-review workshop will be held at Marriott Courtyard 
Arlington Crystal City/Reagan National Airport, 2899 Jefferson Davis 
Highway, Arlington, VA 22202, telephone 703-549-3434. The EPA 
contractor, Versar, Inc. is organizing, convening, and conducting the 
peer-review workshop. To attend the workshop, register by December 7, 
2009, by calling Versar, Inc. at 703-750-3000 extension 6897, sending a 
facsimile to 703-642-6954 or sending an e-mail to hriester@versar.com. 
You may also register via the Internet at http://epa.versar.com/hydrogencyanide.
    The draft ``Toxicological Review of Hydrogen Cyanide and Cyanide 
Salts: In Support of Summary Information on the Integrated Risk 
Information System (IRIS)'' is available primarily via the Internet on 
the National Center for Environmental Assessment's home page under the 
Recent Additions and Publications menus at http://www.epa.gov/ncea. A 
limited number of paper copies are available from the Information 
Management Team, NCEA; telephone: 703-347-8561; facsimile: 703-347-
8691. If you are requesting a paper copy, please provide your name, 
mailing address, and the document title, ``Toxicological Review of 
Hydrogen Cyanide and Cyanide Salts: In Support of Summary Information 
on the Integrated Risk Information System (IRIS).'' Copies are not 
available from Versar, Inc.
    Information on Services for Individuals with Disabilities: EPA 
welcomes public attendance at the ``Hydrogen Cyanide and Cyanide Salts 
peer-review workshop'' and will make every effort to accommodate 
persons with disabilities. For information on access or services for 
individuals with disabilities, please contact Versar, Inc, preferably 
at least 10 days prior to the meeting, to give as much time as possible 
to process your request.

FOR FURTHER INFORMATION CONTACT: Questions regarding information, 
registration, access or services for individuals with disabilities, or 
logistics for the external peer-review workshop should be directed to 
Versar.
    If you have questions about the document, please contact Kathleen 
Newhouse, National Center for Environmental Assessment (NCEA), (8601P) 
1200 Pennsylvania Ave., Washington DC, 20460; telephone: 703-347-8641; 
facsimile: 703-347-8689; or e-mail: newhouse.kathleen@epa.gov.

SUPPLEMENTARY INFORMATION:

I. Information About IRIS

    IRIS is a database that contains potential adverse human health 
effects information that may result from chronic (or lifetime) exposure 
to specific chemical substances found in the environment. The database 
(available on the Internet at http://www.epa.gov/iris) contains 
qualitative and quantitative health effects information for more than 
540 chemical substances that may be used to support the first two steps 
(hazard identification and dose-response evaluation) of a risk 
assessment process. When supported by available data, the database 
provides oral reference doses (RfDs) and inhalation reference 
concentrations (RfCs) for chronic health effects, and oral slope 
factors and inhalation unit risks for carcinogenic effects. Combined 
with specific exposure information, government and private entities can 
use IRIS data to help characterize public health risks of chemical 
substances in a site-specific situation and thereby support risk 
management decisions designed to protect public health.

    Dated: October 29, 2009.
Rebecca Clark,
Acting Director, National Center for Environmental Assessment.
[FR Doc. E9-27051 Filed 11-9-09; 8:45 am]
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