[Federal Register Volume 76, Number 214 (Friday, November 4, 2011)]
[Notices]
[Pages 68460-68461]
From the Federal Register Online via the Government Printing Office [www.gpo.gov]
[FR Doc No: 2011-28619]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Office of the Secretary
Findings of Research Misconduct
AGENCY: Office of the Secretary, HHS.
ACTION: Notice.
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SUMMARY: Notice is hereby given that the Office of Research Integrity
(ORI) has taken final action in the following case:
Jayant Jagannathan, M.D., University of Virginia Medical Center:
Based on the report of an investigation conducted by the University of
Virginia (UVA) and additional analysis conducted by ORI in its
oversight review, ORI found that Dr. Jayant Jagannathan, former
Resident Physician at UVA Medical Center, engaged in research
misconduct by plagiarizing research supported by National Institutes of
Health (NIH) research and training awards and by NIH intramural
research funds from the National Institute of Neurological Disorders
and Stroke (NINDS), Surgical Neurosurgery Branch (NSB), and from the
National Institute of Dental and Craniofacial Research (NIDCR).
ORI found that the Respondent engaged in research misconduct by
including, in five publications, large amounts of text and an
illustration that he plagiarized from publications supported by the
following NIH grant awards: T32 CA09677, P01 HL024136, R01 HL059157,
P50 CA090270, M01 RR01346, R01 CA075979, R01 DK064169, R01 NS027544,
R01 NS052406, and K08 NS002197,\1\ and by intramural funds from the
Surgical Neurosurgery Branch, NINDS, and from NIDCR.
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\1\ T32 CA09677, Radiation Biology Training Grant,'' A. Kennedy,
P.I.
P01 HL024136, ``Mechanisms of Remodeling in Chronic Airway
Inflammation,'' G. Caughey, P.I.
HL059157, ``Angioproteins in Airway Vascular Leak and
Angiogenesis,'' D. McDonald, P.I.
P50 CA090270, ``UTMDACC Cancer Center SPORE in prostate
cancer,'' C. Logothetis, P.I.
M01 RR01346, ``UTHSC GCRC,'' R. Clark, P.I.
R01 CA075979, ``Mechanisms for Pituitary Tumorigenesis,'' S.
Melmed, P.I.
R01 DK064169, ``Metabolic Consequences of Sccurin Disruption,''
S. Melmed, P.I.
R01 NS027544, ``Loss of Developmental Plasticity after Head
Injury,'' D.A. Hovda, P.I.
R01 NS052406, ``Age-dependent Ketone Metabolism after Brain
Injury,'' M.L. Prims, P.I.
K08 NS002197, ``NMDA Receptor Dysfunction after Traumatic Brain
Injury,'' C.C. Christopher, P.I.
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Publications in which Respondent reported plagiarized material
were:
1. Jagannathan, J., Li, J., Szerlip, N., Vortmeyer, A.O.,
Lonser, R.R., Oldfied, E.H., Zhuang, Z. ``Application and
implementation of selective tissue microdissection and proteomic
profiling in neurological disease.'' Neurosurgery 64:4-14, 2009 (to
be retracted);
2. Jagannathan, J., Prevedello, D.M., Dumont, A.S., Laws, E.R.
``Cellular Signaling Molecules as Therapeutic Targets in the
Treatment of Glioblastoma Multiforme.'' Neurosurgical Focus
20(4):E8, 2006 (retracted ``due to plagiarism,'' Neurosurgical Focus
30(2):E8r, 2011);
3. Kanter, A.S., Jagannathan, J., Shaffrey, C.I., Ouellet, J.A.,
Mummaneni, P.V. ``Inflammatory and dysplastic lesions involving the
spine.'' Neurosurgical Clinics of North America 19(1):93-109, 2008;
4. Jagannathan, J., Dumont, A.S., Prevedello, D.M., Oskouian,
R.J., Lopes, B., Jane, J.A. Jr, Laws, E.R. Jr. ``Genetics of
pituitary adenomas: Current theories and future implications.''
Neurosurgical Focus 19(5):E4, 2005 (retracted ``due to plagiarism,''
Neurosurgical Focus 30(2):E4r, 2011);
5. Jagannathan, J. ``Role of calcium influx and modulation of
local neurotransmitters as hallmarks of pediatric traumatic brain
injury.'' Biomarkers Med. 3:95-97, 2009 (retracted online 9/11/
2010).
Dr. Jagannathan has entered into a Voluntary Settlement Agreement
(Agreement) and has voluntarily agreed for a period of four (4) years,
beginning on October 20, 2011:
(1) To have his research supervised; Respondent agreed to ensure
that prior to the submission of an application for U.S. Public Health
Service (PHS) support for a research project on which his participation
is proposed and prior
[[Page 68461]]
to his participation in any capacity on PHS-supported research, the
institution employing him must submit a plan for supervision of his
duties to ORI for approval; the plan for supervision must be designed
to ensure the scientific integrity of his research contribution;
Respondent agreed that he will not participate in any PHS-supported
research after sixty (60) days from the effective date of the Agreement
until a plan for supervision is submitted to and approved by ORI;
Respondent agreed to maintain responsibility for compliance with the
agreed upon supervision plan;
(2) That any institution employing him must submit, in conjunction
with each application for PHS funds, or report, manuscript, or abstract
involving PHS-supported research in which Respondent is involved, a
certification to ORI that the data provided by Respondent are based on
actual experiments or are otherwise legitimately derived and that the
data, procedures, and methodology are accurately reported in the
application, report, manuscript, or abstract;
(3) To submit a letter to the journal editor for publication 3
(Neurosurgical Clinics of North America) listed above, requesting that
the paper be retracted because Respondent had plagiarized portions of
text reported in it; the letter must be sent to ORI for approval prior
to being sent to the editor; and
(4) To exclude himself from serving in any advisory capacity to PHS
including, but not limited to, service on any PHS advisory committee,
board, and/or peer review committee, or as a consultant.
FOR FURTHER INFORMATION CONTACT: Director, Division of Investigative
Oversight, Office of Research Integrity, 1101 Wootton Parkway, Suite
750, Rockville, MD 20852, (240) 453-8800.
John Dahlberg,
Director, Division of Investigative Oversight, Office of Research
Integrity.
[FR Doc. 2011-28619 Filed 11-3-11; 8:45 am]
BILLING CODE 4150-31-P