[Federal Register Volume 78, Number 232 (Tuesday, December 3, 2013)]
[Notices]
[Pages 72682-72683]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2013-28985]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health
Proposed Collection; 60-Day Comment Request; Rapid Throughput
Standardized Evaluation of Transmissible Risk for Substance Use
Disorder in Youth
SUMMARY: In compliance with the requirement of Section 3506(c)(2)(A) of
the Paperwork Reduction Act of 1995, for opportunity for public comment
on proposed data collection projects, the National Institute on Drug
Abuse (NIDA), the National Institutes of Health (NIH), will publish
periodic summaries of proposed projects to be submitted to the Office
of Management and Budget (OMB) for review and approval.
Written comments and/or suggestions from the public and affected
agencies are invited on one or more of the following points: (1)
Whether the proposed collection of information is necessary for the
proper performance of the function of the agency, including whether the
information will have practical utility; (2) The accuracy of the
agency's estimate of the burden of the proposed collection of
information, including the validity of the methodology and assumptions
used; (2) Ways to enhance the quality, utility, and clarity of the
information to be collected; and (4) Ways to minimize the burden of the
collection of information on those who are to respond, including the
use of appropriate automated, electronic, mechanical or other
technological collection techniques or other forms of information
technology.
To Submit Comments and For Further Information: To obtain a copy of
the data collection plans and instructions, contact Dr. Augie Diana,
Health Scientist Administrator, Prevention Research Branch, Division of
Epidemiology, Services, and Prevention Research, NIDA, NIH, 6001
Executive Boulevard, Room 5163, Bethesda, MD 20892, or call non-toll-
free number (301) 443-1942 or Email your request, including your
address to: [email protected]. Formal request for additional plans
and instruments must be requested in writing.
DATES: Comments Due Date: Comments regarding this information
collection are best assured of having their full effect if received
within 60 days of the data of this publication.
Proposed Collection: Rapid Throughput Standardized Evaluation of
Transmissible Risk for Substance Use Disorder in Youth, 0925-New,
National Institute on Drug Abuse (NIDA), National Institutes of Health
(NIH).
Need and Use of Information Collection: This study will finalize
the development of the Transmissible Liability Index (TLI), thereby
advancing the TLI from a research tool to a practical instrument. The
TLI is a psychometric tool for detecting youth at elevated risk for
substance use disorder (SUD). The TLI, a web-based platform for
assessing risk of SUD, is a highly efficient tool both in terms of the
limited time commitment required as well as its low cost. The
inexpensive and high efficiency of the TLI for identifying youths in
need of prevention, and the strong cost-benefits to society for SUD
prevention, portend strong demand for use in a variety of populations
including family and social services, schools, mental health
facilities, and youth protection agencies. To transform the TLI
prototype into a practical instrument, three core tasks remain: (1)
Standardization on a sample (N = 5,000) that is representative of the
general population to generate norms that are specific to age, gender
and ethnicity; (2) Construct validity analysis using standard
parametric modeling techniques to show that heritability accounts for
the major portion of variance on TLI scores; the sample (150 identical
and 150 fraternal twins) will be representative of the same general
population characteristics identified above; and (3) Psychometric
analysis of validity and reliability based on the above data.
Validating the TLI furthers NIDA's mission by legitimating the tool for
exploring the attitudes and social predictors of addictive behaviors
with the intention of reducing or eliminating drug-taking behavior.
This research is squarely within NIDA's mission of research on drug
abuse and addiction, as well as its focus on ensuring the rapid and
effective dissemination and use of the results to significantly improve
efforts to stem substance use disorder. To move the TLI from the
research domain to practical use through commercial dissemination, the
research and development team (``the R&D team'') needs to satisfy
professional quality standards consistent with American Psychological
Association regulations. To satisfy those standards, the R&D team must
demonstrate the reliability and internal validity of the TLI against
existing standardized psychometric studies for youth populations, ages
14 to 18. The 14-to-18 year old age range was selected because it
encompasses the years typically spent in high school, which are known
to be the timeframe when substance use is
[[Page 72683]]
likely to begin and accelerates, often leading to substance abuse
disorder. Notably, the peak period for the manifestation of cannabis-
use disorder is age 18-19, and the past-year-prevalence for alcohol-use
disorder is age 20-22. The TLI is designed to identify the propensity
for these and other substance abuse prior to manifestation; as such,
collecting data from the high school age group (14-18 years old) is
critical to identifying at-risk youths for the purposes of early
intervention. Thus, the TLI must be tested with data collected from
youth populations, ages 14 to 18, comparable to those in existing
studies. Moreover, the R&D team must provide psychometric external
validation for the TLI through data collection from sets of identical
and fraternal twins. Psychometric analyses are required to show that
the TLI performs according to expectations. Accordingly, studies will
be performed on the collected information to demonstrate i) construct,
ii) discriminative, iii) concurrent, and iv) predictive validity.
OMB approval is requested for 2 years. There are no costs to
respondents other than their time. The total estimated annualized
burden hours are 3,083.
Estimated Annualized Burden Hours
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Average burden
Type of respondent: individuals and households Number of Responses per per response Annual hour
respondents respondent (in hours) burden
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Parent of 14-17 year-old students: Consent Form. 5,000 1 1/60 83
14-18 year-old students: School Survey (TLI).... .............. 1 30/60 2,500
14-18 year-old youths or their parents: Consent 600 1 1/60 10
Form...........................................
14-18 year-old youths: Twins Survey (Demo/D&A).. .............. 1 10/60 100
14-18 year-old youths: Twins Survey .............. 1 10/60 100
(Dysregulation)................................
14-18 year-old youths: Twins Survey (TLI)....... .............. 1 29/60 290
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Dated: November 20, 2013.
Glenda J. Conroy,
Executive Officer (OM Director), NIDA, NIH.
[FR Doc. 2013-28985 Filed 12-2-13; 8:45 am]
BILLING CODE 4140-01-P