Subpart A—General Provisions
§ 582.1
Substances that are generally recognized as safe.
(a) It is impracticable to list all substances that are generally recognized as safe for their intended use. However, by way of illustration, the Commissioner regards such common food ingredients as salt, pepper, sugar, vinegar, baking powder, and monosodium glutamate as safe for their intended use. The lists in subparts B through H of this part include additional substances that, when used for the purposes indicated, in accordance with good manufacturing or feeding practice, are regarded by the Commissioner as generally recognized as safe for such uses.
(b) For the purposes of this section, good manufacturing or feeding practice shall be defined to include the following restrictions:
(1) The quantity of a substance added to animal food does not exceed the amount reasonably required to accomplish its intended physical, nutritional, or other technical effect in food; and
(2) The quantity of a substance that becomes a component of animal food as a result of its use in the manufacturing, processing, or packaging of food, and which is not intended to accomplish any physical or other technical effect in the food itself, shall be reduced to the extent reasonably possible.
(3) The substance is of appropriate grade and is prepared and handled as a food ingredient. Upon request the Commissioner will offer an opinion, based on specifications and intended use, as to whether or not a particular grade or lot of the substance is of suitable purity for use in food and would generally be regarded as safe for the purpose intended, by experts qualified to evaluate its safety.
(c) The inclusion of substances in the list of nutrients does not constitute a finding on the part of the Department that the substance is useful as a supplement to the diet for animals.
(d) Substances that are generally recognized as safe for their intended use within the meaning of section 409 of the Act are listed in subparts B through H of this part. When the status of a substance has been reevaluated and affirmed as GRAS or deleted from subparts B through H of this part, an appropriate explanation will be noted, e.g., “affirmed as GRAS,” “food additive regulation,” “interim food additive regulation,” or “prohibited from use in food,” with a reference to the appropriate new regulation. Such notation will apply only to the specific use covered by the review, e.g., direct animal food use and/or indirect animal food use and/or animal feed use and will not affect its status for other uses not specified in the referenced regulation, pending a specific review of such other uses.
§ 582.10
Spices and other natural seasonings and flavorings.
Spices and other natural seasonings and flavorings that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:
Common name
Botanical name of plant source
Alfalfa herb and seed
Medicago sativa L.
Allspice
Pimenta officinalis Lindl.
Ambrette seed
Hibiscus abelmoschus L.
Angelica
Angelica archangelica L. or other spp. of Angelica.
Angelica root
Do.
Angelica seed
Do.
Angostura (cusparia bark)
Galipea officinalis Hancock.
Anise
Pimpinella anisum L.
Anise, star
Illicium verum Hook. f.
Balm (lemon balm)
Melissa officinalis L.
Basil, bush
Ocimum minimum L.
Basil, sweet
Ocimum basilicum L.
Bay
Laurus nobilis L.
Calendula
Calendula officinalis L.
Camomile (chamomile), English or Roman
Anthemis nobilis L.
Camomile (chamomile), German or Hungarian
Matricaria chamomilla L.
Capers
Capparis spinosa L.
Capsicum
Capsicum frutescens L. or Capsicum annuum L.
Caraway
Carum carvi L.
Caraway, black (black cumin)
Nigella sativa L.
Cardamom (cardamon)
Elettaria cardamomum Maton.
Cassia, Chinese
Cinnamomum cassia Blume.
Cassia, Padang or Batavia
Cinnamomum burmanni Blume.
Cassia, Saigon
Cinnamomum loureirii Nees.
Cayenne pepper
Capsicum frutescens L. or Capsicum annuum L.
Celery seed
Apium graveolens L.
Chervil
Anthriscus cerefolium (L.) Hoffm.
Chives
Allium schoenoprasum L.
Cinnamon, Ceylon
Cinnamomum zeylanicum Nees.
Cinnamon, Chinese
Cinnamomum cassia Blume.
Cinnamon, Saigon
Cinnamomum loureirii Nees.
Clary (clary sage)
Salvia sclarea L.
Clover
Trifolium spp.
Cloves
Eugenia caryophyllata Thunb.
Coriander
Coriandrum sativum L.
Cumin (cummin)
Cuminum cyminum L.
Cumin, black (black caraway)
Nigella sativa L.
Dill
Anethum graveolens L.
Elder flowers
Sambucus canadensis L.
Fennel, common
Foeniculum vulgare Mill.
Fennel, sweet (finocchio, Florence fennel)
Foeniculum vulgare Mill. var. duice (DC.) Alex.
Fenugreek
Trigonella foenum-graecum L.
Galanga (galangal)
Alpina officinarum Hance.
Garlic
Allium sativum L.
Geranium
Pelargonium spp.
Ginger
Zingiber officinale Rosc.
Glycyrrhiza
Glycyrrhiza glabra L. and other spp. of Glycyrrhiza.
Grains of paradise
Amomum melegueta Rosc.
Horehound (hoarhound)
Marrubium vulgare L.
Horseradish
Armoracia lapathifolia Gilib.
Hyssop
Hyssopus officinalis L.
Lavender
Lavandula officinalis Chaix.
Licorice
Glycyrrhiza glabra L. and other spp. of Glycyrrhiza.
Linden flowers
Tilia spp.
Mace
Myristica fragrans Houtt.
Marigold, pot
Calendula officinalis L.
Marjoram, pot
Majorana onites (L.) Benth.
Marjoram, sweet
Majorana hortensis Moench.
Mustard, black or brown
Brassica nigra (L.) Koch.
Mustard, brown
Brassica juncea (L.) Coss.
Mustard, white or yellow
Brassica hirta Moench.
Nutmeg
Myristica fragrans Houtt.
Oregano (oreganum, Mexican oregano, Mexican sage, origan)
Lippia spp.
Paprika
Capsicum annuum L.
Parsley
Petroselinum crispum (Mill.) Mansf.
Pepper, black
Piper nigrum L.
Pepper, cayenne
Capsicum frutescens L. or Capsicum annuum L.
Pepper, red
Do.
Pepper, white
Piper nigrum L.
Peppermint
Mentha piperita L.
Poppy seed
Papaver somniferum L.
Pot marigold
Calendula officinalis L.
Pot marjoram
Majorana onites (L.) Benth.
Rosemary
Rosmarinus officinalis L.
Rue
Ruta graveolens L.
Saffron
Crocus sativus L.
Sage
Salvia officinalis L.
Sage, Greek
Salvia triloba L.
Savory, summer
Satureia hortensis L. (Satureja).
Savory, winter
Satureia montana L. (Satureja).
Sesame
Sesamum indicum L.
Spearmint
Mentha spicata L.
Star anise
Illicium verum Hook. f.
Tarragon
Artemisia dracunculus L.
Thyme
Thymus vulgaris L.
Thyme, wild or creeping
Thymus serpyllum L.
Turmeric
Curcuma longa L.
Vanilla
Vanilla planifolia Andr. or Vanilla tahitensis J. W. Moore.
Zedoary
Curcuma zedoaria Rosc.
§ 582.20
Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
Essential oils, oleoresins (solvent-free), and natural extractives (including distillates) that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:
Common name
Botanical name of plant source
Alfalfa
Medicago sativa L.
Allspice
Pimenta officinalis Lindl.
Almond, bitter (free from prussic acid)
Prunus amygdalus Batsch, Prunus armeniaca L. or Prunus persica (L.) Batsch.
Ambrette (seed)
Hibiscus moschatus Moench.
Angelica root
Angelica archangelica L.
Angelica seed
Do.
Angelica stem
Do.
Angostura (cusparia bark)
Galipea officinalis Hancock.
Anise
Pimpinella anisum L.
Asafetida
Ferula assa-foetida L. and related spp. of Ferula.
Balm (lemon balm)
Melissa officinalis L.
Balsam of Peru
Myroxylon pereirae Klotzsch.
Basil
Ocimum basilicum L.
Bay leaves
Laurus nobilis L.
Bay (myrcia oil)
Pimenta racemosa (Mill.) J. W. Moore.
Bergamot (bergamot orange)
Citrus aurantium L. subsp. bergamia Wright et Arn.
Bitter almond (free from prussic acid)
Prunus amygdalus Batsch, Prunus armeniaca L., or Prunus persica (L.) Batsch.
Bois de rose
Aniba rosaeodora Ducke.
Cacao
Theobroma cacao L.
Camomile (chamomile) flowers, Hungarian
Matricaria chamomilla L.
Camomile (chamomile) flowers, Roman or English
Anthemis nobilis L.
Cananga
Cananga odorata Hook. f. and Thoms.
Capsicum
Capsicum frutescens L. and Capsicum annuum L.
Caraway
Carum carvi L.
Cardamom seed (cardamon)
Elettaria cardamomum Maton.
Carob bean
Ceratonia siliqua L.
Carrot
Daucus carota L.
Cascarilla bark
Croton eluteria Benn.
Cassia bark, Chinese
Cinnamomum cassia Blume.
Cassia bark, Padang or Batavia
Cinnamomum burmanni Blume.
Cassia bark, Saigon
Cinnamomum loureirii Nees.
Celery seed
Apium graveolens L.
Cherry, wild, bark
Prunus serotina Ehrh.
Chervil
Anthriscus cerefolium (L.) Hoffm.
Chicory
Cichorium intybus L.
Cinnamon bark, Ceylon
Cinnamomum zeylanicum Nees.
Cinnamon bark, Chinese
Cinnamomum cassia Blume.
Cinnamon bark, Saigon
Cinnamomum loureirii Nees.
Cinnamon leaf, Ceylon
Cinnamomum zeylanicum Nees.
Cinnamon leaf, Chinese
Cinnamomum cassia Blume.
Cinnamon leaf, Saigon
Cinnamomum loureirii Nees.
Citronella
Cymbopogon nardus Rendle.
Citrus peels
Citrus spp.
Clary (clary sage)
Salvia sclarea L.
Clove bud
Eugenia caryophyllata Thunb.
Clove leaf
Do.
Clove stem
Do.
Clover
Trifolium spp.
Coca (decocainized)
Erythroxylum coca Lam. and other spp. of Erythroxylum.
Coffee
Coffea spp.
Cola nut
Cola acuminata Schott and Endl., and other spp. of Cola.
Coriander
Coriandrum sativum L.
Corn silk
Zea mays L.
Cumin (cummin)
Cuminum cyminum L.
Curacao orange peel (orange, bitter peel)
Citrus aurantium L.
Cusparia bark
Galipea officinalis Hancock.
Dandelion
Taraxacum officinale Weber and T. laevigatum DC.
Dandelion root
Do.
Dill
Anethum graveolens L.
Dog grass (quackgrass, triticum)
Agropyron repens (L.) Beauv.
Elder flowers
Sambucus canadensis L. and S. nigra L.
Estragole (esdragol, esdragon, tarragon)
Artemisia dracunculus L.
Estragon (tarragon)
Do.
Fennel, sweet
Foeniculum vulgare Mill.
Fenugreek
Trigonella foenum-graecum L.
Galanga (galangal)
Alpinia officinarum Hance.
Garlic
Allium sativum L.
Geranium
Pelargonium spp.
Geranium, East Indian
Cymbopogon martini Stapf.
Geranium, rose
Pelargonium graveolens L'Her.
Ginger
Zingiber officinale Rosc.
Glycyrrhiza
Glycyrrhiza glabra L. and other spp. of Glycyrrhiza.
Glycyrrhizin, ammoniated
Do.
Grapefruit
Citrus paradisi Macf.
Guava
Psidium spp.
Hickory bark
Carya spp.
Horehound (hoarhound)
Marrubium vulgare L.
Hops
Humulus lupulus L.
Horsemint
Monarda punctata L.
Hyssop
Hyssopus officinalis L.
Immortelle
Helichrysum augustifolium DC.
Jasmine
Jaminum officinale L. and other spp. of Jasminum.
Juniper (berries)
Juniperus communis L.
Kola nut
Cola acuminata Schott and Endl., and other spp. of Cola.
Laurel berries
Laurus nobilis L.
Laurel leaves
Laurus spp.
Lavender
Lavandula officinalis Chaix.
Lavender, spike
Lavandula latifolia Vill.
Lavandin
Hybrids between Lavandula officinalis Chaix and Lavandula latifolin Vill.
Lemon
Citrus limon (L.) Burm. f.
Lemon balm (see balm).
Lemon grass
Cymbopogon citratus DC. and Cymbopogon flexuosus Stapf.
Lemon peel
Citrus limon (L.) Burm. f.
Licorice
Glycyrrhiza glabra L. and other spp. of Glycyrrhiza.
Lime
Citrus aurantifolia Swingle.
Linden flowers
Tilia spp.
Locust bean
Ceratonia siliqua L.
Lupulin
Humulus lupulus L.
Mace
Myristica fragrans Houtt.
Malt (extract)
Hordeum vulgare L., or other grains.
Mandarin
Citrus reticulata Blanco.
Marjoram, sweet
Majorana hortensis Moench.
Mate 1
Ilex paraguariensis St. Hil.
Melissa (see balm).
Menthol
Mentha spp.
Menthyl acetate
Do.
Molasses (extract)
Saccharum officinarum L.
Mustard
Brassica spp.
Naringin
Citrus paradisi Macf.
Neroli, bigarade
Citrus aurantium L.
Nutmeg
Myristica fragrans Houtt.
Onion
Allium cepa L.
Orange, bitter, flowers
Citrus aurantium L.
Orange, bitter, peel
Do.
Orange leaf
Citrus sinensis (L.) Osbeck.
Orange, sweet
Do.
Orange, sweet, flowers
Do.
Orange, sweet, peel
Do.
Origanum
Origanum spp.
Palmarosa
Cymbopogon martini Stapf.
Paprika
Capsicum annuum L.
Parsley
Petroselinum crispum (Mill.) Mansf.
Pepper, black
Piper nigrum L.
Pepper, white
Piper nigrum L.
Peppermint
Mentha piperita L.
Peruvian balsam
Myroxylon pereirae Klotzsch.
Petitgrain
Citrus aurantium L.
Petitgrain lemon
Citrus limon (L.) Burm. f.
Petitgrain mandarin or tangerine
Citrus reticulata Blanco.
Pimenta
Pimenta officinalis Lindl.
Pimenta leaf
Primenta officinalis Lindl.
Pipsissewa leaves
Chimaphila umbellata Nutt.
Pomegranate
Punica granatum L.
Prickly ash bark
Xanthoxylum (or Zanthoxylum) Americanum Mill. or Xanthoxylum clava-herculis L.
Rose absolute
Rosa alba L., Rosa centifolia L., Rosa damascena Mill., Rosa gallica L., and vars. of these spp.
Rose (otto of roses, attar of roses)
Do.
Rose buds
Do.
Rose flowers
Do.
Rose fruit (hips)
Do.
Rose geranium
Pelargonium graveolens L'Her.
Rose leaves
Rosa spp.
Rosemary
Rosmarinus officinalis L.
Rue
Ruta graveolens L.
Saffron
Crocus sativus L.
Sage
Salvia officinalis L.
Sage, Greek
Salvia triloba L.
Sage, Spanish
Salvia lavandulaefolia Vahl.
St. John's bread
Ceratonia siliqua L.
Savory, summer
Satureia hortensis L.
Savory, winter
Satureia montana L.
Schinus molle
Schinus molle L.
Sloe berries (blackthorn berries)
Prunus spinosa L.
Spearmint
Mentha spicata L.
Spike lavender
Lavandula latifolia Vill.
Tamarind
Tamarindus indica L.
Tangerine
Citrus reticulata Blanco.
Tannic acid
Nutgalls of Quercus infectoria Oliver and related spp. of Quercus. Also in many other plants.
Tarragon
Artemisia dracunculus L.
Tea
Thea sinensis L.
Thyme
Thymus vulgaris L. and Thymus zygis var. gracilis Boiss.
Thyme, white
Do.
Thyme, wild or creeping
Thymus serpyllum L.
Triticum (see dog grass).
Tuberose
Polianthes tuberosa L.
Turmeric
Curcuma longa L.
Vanilla
Vanilla planifolia Andr. or Vanilla tahitensis J. W. Moore.
Violet flowers
Viola odorata L.
Violet leaves
Do.
Violet leaves absolute
Do.
Wild cherry bark
Prunus serotina Ehrh.
Ylang-ylang
Cananga odorata Hook. f. and Thoms.
Zedoary bark
Curcuma zedoaria Rosc.
§ 582.30
Natural substances used in conjunction with spices and other natural seasonings and flavorings.
Natural substances used in conjunction with spices and other natural seasonings and flavorings that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:
Common name
Botanical name of plant source
Algae, brown (kelp)
Laminaria spp. and Nereocystis spp.
Algae, red
Porphyra spp. and Rhodymenia palmata (L.) Grev.
Dulse
Rhodymenia palmata (L.)
§ 582.40
Natural extractives (solvent-free) used in conjunction with spices, seasonings, and flavorings.
Natural extractives (solvent-free) used in conjunction with spices, seasonings, and flavorings that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:
Common name
Botanical name of plant source
Algae, brown
Laminaria spp. and Nereocystis spp.
Algae, red
Porphyra spp. and Rhodymenia palmata (L.) Grev.
Apricot kernel (persic oil)
Prunus armeniaca L.
Dulse
Rhodymenia palmata (L.) Grev.
Kelp (see algae, brown).
Peach kernel (persic oil)
Prunus persica Sieb. et Zucc.
Peanut stearine
Arachis hypogaea L.
Persic oil (see apricot kernel and peach kernel).
Quince seed
Cydonia oblonga Miller.
§ 582.50
Certain other spices, seasonings, essential oils, oleoresins, and natural extracts.
Certain other spices, seasonings, essential oils, oleoresins, and natural extracts that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:
Common name
Derivation
Ambergris
Physeter macrocephalus L.
Castoreum
Castor fiber L. and C. canadensis Kuhl.
Civet (zibeth, zibet, zibetum)
Civet cats, Viverra civetta Schreber and Viverra zibetha Schreber.
Cognac oil, white and green
Ethyl oenanthate, so-called.
Musk (Tonquin musk)
Musk deer, Moschus moschiferus L.
§ 582.60
Synthetic flavoring substances and adjuvants.
Synthetic flavoring substances and adjuvants that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:
Acetaldehyde (ethanal).
Acetoin (acetyl methylcarbinol).
Aconitic acid (equisetic acid, citridic acid, achilleic acid).
Anethole (parapropenyl anisole).
Benzaldehyde (benzoic aldehyde).
N-Butyric acid (butanoic acid).
d- or l-Carvone (carvol).
Cinnamaldehyde (cinnamic aldehyde).
Citral (2,6-dimethyloctadien-2,6-al-8, geranial, neral).
Decanal (N-decylaldhehyde, capraldehyde, capric aldehyde, caprinaldehyde, aldehyde C-10).
Diacetyl (2,3-butandeione). Ethyl acetate. Ethyl butyrate.
3-Methyl-3-phenyl glycidic acid ethyl ester (ethyl-methyl-phenyl-glycidate, so-called strawberry aldehyde, C-16 aldehyde).
Ethyl vanillin.
Eugenol.
Geranoil (3,7-dimethyl-2,6 and 3,6-octadien-1-ol).
Geranyl acetate (geraniol acetate).
Glycerol (glyceryl) tributyrate (tributyrin, butyrin).
Limonene (d-, l-, and dl-).
Linalool (linalol, 3,7-dimethyl-1,6-octadien-3-ol).
Linalyl acetate (bergamol).
1-Malic acid.
Methyl anthranilate (methyl-2-aminobenzoate).
Piperonal (3,4-methylenedioxy-benzaldehyde, heliotropin).
Vanillin.
§ 582.80
Trace minerals added to animal feeds.
These substances added to animal feeds as nutritional dietary supplements are generally recognized as safe when added at levels consistent with good feeding practice.1
1 All substances listed may be in anhydrous or hydrated form.
Element
Source compounds
Cobalt
Cobalt acetate.
Cobalt carbonate.
Cobalt chloride.
Cobalt oxide.
Cobalt sulfate.
Copper
Copper carbonate.
Copper chloride.
Copper gluconate.
Copper hydroxide.
Copper orthophosphate.
Copper oxide.
Copper pyrophosphate.
Copper sulfate.
Iodine
Calcium iodate.
Calcium iodobehenate.
Cuprous iodide.
3,5-Diiodosalicylic acid.
Ethylenediamine dihydroiodide.
Potassium iodate.
Potassium iodide.
Sodium iodate.
Sodium iodide.
Thymol iodide.
Iron
Iron ammonium citrate.
Iron carbonate.
Iron chloride.
Iron gluconate.
Iron oxide.
Iron phosphate.
Iron pyrophosphate.
Iron sulfate.
Reduced iron.
Manganese
Manganese acetate.
Manganese carbonate.
Manganese citrate (soluble).
Manganese chloride.
Manganese gluconate.
Manganese orthophosphate.
Manganese phosphate (dibasic).
Manganese sulfate.
Manganous oxide.
Zinc
Zinc acetate.
Zinc carbonate.
Zinc chloride.
Zinc oxide.
Zinc sulfate.
§ 582.99
Adjuvants for pesticide chemicals.
Adjuvants, identified and used in accordance with 40 CFR 180.1001(c) and (d), which are added to pesticide use dilutions by a grower or applicator prior to application to the raw agricultural commodity, are exempt from the requirement of tolerances under section 409 of the act.
Subpart B—General Purpose Food Additives
§ 582.1005
Acetic acid.
(a) Product. Acetic acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1009
Adipic acid.
(a) Product. Adipic acid.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a buffer and neutralizing agent in accordance with good manufacturing or feeding practice.
§ 582.1033
Citric acid.
(a) Product. Citric acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1057
Hydrochloric acid.
(a) Product. Hydrochloric acid.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a buffer and neutralizing agent in accordance with good manufacturing or feeding practice.
§ 582.1061
Lactic acid.
(a) Product. Lactic acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1069
Malic acid.
(a) Product. Malic acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1073
Phosphoric acid.
(a) Product. Phosphoric acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1077
Potassium acid tartrate.
(a) Product. Potassium acid tartrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1087
Sodium acid pyrophosphate.
(a) Product. Sodium acid pyrophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1091
Succinic acid.
(a) Product. Succinic acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1095
Sulfuric acid.
(a) Product. Sulfuric acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1099
Tartaric acid.
(a) Product. Tartaric acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1125
Aluminum sulfate.
(a) Product. Aluminum sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1127
Aluminum ammonium sulfate.
(a) Product. Aluminum ammonium sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1129
Aluminum potassium sulfate.
(a) Product. Aluminum potassium sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1131
Aluminum sodium sulfate.
(a) Product. Aluminum sodium sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1135
Ammonium bicarbonate.
(a) Product. Ammonium bicarbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1137
Ammonium carbonate.
(a) Product. Ammonium carbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1139
Ammonium hydroxide.
(a) Product. Ammonium hydroxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1141
Ammonium phosphate.
(a) Product. Ammonium phosphate (mono- and dibasic).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1143
Ammonium sulfate.
(a) Product. Ammonium sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1155
Bentonite.
(a) Product. Bentonite.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1165
Butane.
(a) Product. Butane.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1191
Calcium carbonate.
(a) Product. Calcium carbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1193
Calcium chloride.
(a) Product. Calcium chloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1195
Calcium citrate.
(a) Product. Calcium citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1199
Calcium gluconate.
(a) Product. Calcium gluconate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1205
Calcium hydroxide.
(a) Product. Calcium hydroxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1207
Calcium lactate.
(a) Product. Calcium lactate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1210
Calcium oxide.
(a) Product. Calcium oxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1217
Calcium phosphate.
(a) Product. Calcium phosphate (mono-, di-, and tribasic).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1235
Caramel.
(a) Product. Caramel.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1240
Carbon dioxide.
(a) Product. Carbon dioxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1275
Dextrans.
(a) Product. Dextrans of average molecular weight below 100,000.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1320
Glycerin.
(a) Product. Glycerin.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1324
Glyceryl monostearate.
(a) Product. Glyceryl monostearate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1355
Helium.
(a) Product. Helium.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1366
Hydrogen peroxide.
(a) Product. Hydrogen peroxide.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a bleaching agent in accordance with good manufacturing or feeding practice.
§ 582.1400
Lecithin.
(a) Product. Lecithin.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1425
Magnesium carbonate.
(a) Product. Magnesium carbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1428
Magnesium hydroxide.
(a) Product. Magnesium hydroxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1431
Magnesium oxide.
(a) Product. Magnesium oxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1480
Methylcellulose.
(a) Product. U.S.P. methylcellulose, except that the methoxy content shall not be less than 27.5 percent and not more than 31.5 percent on a dry-weight basis.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1500
Monoammonium glutamate.
(a) Product. Monoammonium glutamate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1516
Monopotassium glutamate.
(a) Product. Monopotassium glutamate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1540
Nitrogen.
(a) Product. Nitrogen.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1585
Papain.
(a) Product. Papain.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1613
Potassium bicarbonate.
(a) Product. Potassium bicarbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1619
Potassium carbonate.
(a) Product. Potassium carbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1625
Potassium citrate.
(a) Product. Potassium citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1631
Potassium hydroxide.
(a) Product. Potassium hydroxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1643
Potassium sulfate.
(a) Product. Potassium sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1655
Propane.
(a) Product. Propane.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1666
Propylene glycol.
(a) Product. Propylene glycol.
(b) Conditions of use. This substance is generally recognized as safe (except in cat food) when used in accordance with good manufacturing or feeding practice.
[41 FR 38657, Sept. 10, 1976, as amended at 61 FR 19544, May 2, 1996]
§ 582.1685
Rennet.
(a) Product. Rennet (rennin).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1711
Silica aerogel.
(a) Product. Silica aerogel as a finely powdered microcellular silica foam having a minimum silica content of 89.5 percent.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a component of antifoaming agents in accordance with good manufacturing or feeding practice.
§ 582.1721
Sodium acetate.
(a) Product. Sodium acetate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1736
Sodium bicarbonate.
(a) Product. Sodium bicarbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1742
Sodium carbonate.
(a) Product. Sodium carbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1745
Sodium carboxymethylcellulose.
(a) Product. Sodium carboxymethyl- cellulose is the sodium salt of carboxymethylcellulose not less than 99.5 percent on a dry-weight basis, with maximum substitution of 0.95 carboxymethyl groups per anhydroglucose unit, and with a minimum viscosity of 25 centipoises for 2 percent by weight aqueous solution at 25° C.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1748
Sodium caseinate.
(a) Product. Sodium caseinate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1751
Sodium citrate.
(a) Product. Sodium citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1763
Sodium hydroxide.
(a) Product. Sodium hydroxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1775
Sodium pectinate.
(a) Product. Sodium pectinate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1778
Sodium phosphate.
(a) Product. Sodium phosphate (mono-, di-, and tribasic).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1781
Sodium aluminum phosphate.
(a) Product. Sodium aluminum phosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1792
Sodium sesquicarbonate.
(a) Product. Sodium sesquicarbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1804
Sodium potassium tartrate.
(a) Product. Sodium potassium tartrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1810
Sodium tripolyphosphate.
(a) Product. Sodium tripolyphosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1901
Triacetin.
(a) Product. Triacetin (glyceryl triacetate).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1973
Beeswax.
(a) Product. Beeswax (yellow wax).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1975
Bleached beeswax.
(a) Product. Bleached beeswax (white wax).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.1978
Carnauba wax.
(a) Product. Carnauba wax.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
Subpart D—Chemical Preservatives
§ 582.3013
Ascorbic acid.
(a) Product. Ascorbic acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3021
Benzoic acid.
(a) Product. Benzoic acid.
(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.
§ 582.3041
Erythorbic acid.
(a) Product. Erythorbic acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3081
Propionic acid.
(a) Product. Propionic acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3089
Sorbic acid.
(a) Product. Sorbic acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3109
Thiodipropionic acid.
(a) Product. Thiodipropionic acid.
(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice.
§ 582.3149
Ascorbyl palmitate.
(a) Product. Ascorbyl palmitate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3169
Butylated hydroxyanisole.
(a) Product. Butylated hydroxyanisole.
(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of food provided the substance is used in accordance with good manufacturing or feeding practice.
§ 582.3173
Butylated hydroxytoluene.
(a) Product. Butylated hydroxytol- uene.
(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of food provided the substance is used in accordance with good manufacturing or feeding practice.
§ 582.3189
Calcium ascorbate.
(a) Product. Calcium ascorbate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3221
Calcium propionate.
(a) Product. Calcium propionate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3225
Calcium sorbate.
(a) Product. Calcium sorbate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3280
Dilauryl thiodipropionate.
(a) Product. Dilauryl thiodipropionate.
(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice.
§ 582.3336
Gum guaiac.
(a) Product. Gum guaiac.
(b) Tolerance. 0.1 percent (equivalent antioxidant activity 0.01 percent).
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in edible fats or oils in accordance with good manufacturing or feeding practice.
§ 582.3490
Methylparaben.
(a) Product. Methylparaben (methyl p-hydroxybenzoate).
(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.
§ 582.3616
Potassium bisulfite.
(a) Product. Potassium bisulfite.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.
§ 582.3637
Potassium metabisulfite.
(a) Product. Potassium metabisulfite.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.
§ 582.3640
Potassium sorbate.
(a) Product. Potassium sorbate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3660
Propyl gallate.
(a) Product. Propyl gallate.
(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice.
§ 582.3670
Propylparaben.
(a) Product. Propylparaben (propyl p-hydroxybenzoate).
(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.
§ 582.3731
Sodium ascorbate.
(a) Product. Sodium ascorbate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3733
Sodium benzoate.
(a) Product. Sodium benzoate.
(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.
§ 582.3739
Sodium bisulfite.
(a) Product. Sodium bisulfite.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.
§ 582.3766
Sodium metabisulfite.
(a) Product. Sodium metabisulfite.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.
§ 582.3784
Sodium propionate.
(a) Product. Sodium propionate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3795
Sodium sorbate.
(a) Product. Sodium sorbate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.3798
Sodium sulfite.
(a) Product. Sodium sulfite.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.
§ 582.3845
Stannous chloride.
(a) Product. Stannous chloride.
(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.0015 percent calculated as tin in accordance with good manufacturing or feeding practice.
§ 582.3862
Sulfur dioxide.
(a) Product. Sulfur dioxide.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.
§ 582.3890
Tocopherols.
(a) Product. Tocopherols.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
Subpart F—Nutrients and/or Dietary Supplements 1
§ 582.5013
Ascorbic acid.
(a) Product. Ascorbic acid.
1 Amino acids listed in this subpart may be free hydrochloride salt, hydrated, or anhydrous form, where applicable.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5017
Aspartic acid.
(a) Product. Aspartic acid (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5049
Aminoacetic acid.
(a) Product. Glycine (aminoacetic acid).
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.
§ 582.5065
Linoleic acid.
(a) Product. Linoleic acid prepared from edible fats and oils and free from chick-edema factor.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5118
Alanine.
(a) Product. Alanine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5145
Arginine.
(a) Product. Arginine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5159
Biotin.
(a) Product. Biotin.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5191
Calcium carbonate.
(a) Product. Calcium carbonate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5195
Calcium citrate.
(a) Product. Calcium citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5201
Calcium glycerophosphate.
(a) Product. Calcium glycerophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5210
Calcium oxide.
(a) Product. Calcium oxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5212
Calcium pantothenate.
(a) Product. Calcium pantothenate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5217
Calcium phosphate.
(a) Product. Calcium phosphate (mono-, di-, and tribasic).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5223
Calcium pyrophosphate.
(a) Product. Calcium pyrophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5230
Calcium sulfate.
(a) Product. Calcium sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5245
Carotene.
(a) Product. Carotene.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5250
Choline bitartrate.
(a) Product. Choline bitartrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5252
Choline chloride.
(a) Product. Choline chloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5260
Copper gluconate.
(a) Product. Copper gluconate.
(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.005 percent in accordance with good manufacturing or feeding practice.
§ 582.5271
Cysteine.
(a) Product. Cysteine (L-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5273
Cystine.
(a) Product. Cystine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5301
Ferric phosphate.
(a) Product. Ferric phosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5304
Ferric pyrophosphate.
(a) Product. Ferric pyrophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5306
Ferric sodium pyrophosphate.
(a) Product. Ferric sodium pyrophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5308
Ferrous gluconate.
(a) Product. Ferrous gluconate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5311
Ferrous lactate.
(a) Product. Ferrous lactate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5315
Ferrous sulfate.
(a) Product. Ferrous sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5361
Histidine.
(a) Product. Histidine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5370
Inositol.
(a) Product. Inositol.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5375
Iron reduced.
(a) Product. Iron reduced.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5381
Isoleucine.
(a) Product. Isoleucine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5406
Leucine.
(a) Product. Leucine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5411
Lysine.
(a) Product. Lysine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5431
Magnesium oxide.
(a) Product. Magnesium oxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5434
Magnesium phosphate.
(a) Product. Magnesium phosphate (di- and tribasic).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5443
Magnesium sulfate.
(a) Product. Magnesium sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5446
Manganese chloride.
(a) Product. Manganese chloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5449
Manganese citrate.
(a) Product. Manganese citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5452
Manganese gluconate.
(a) Product. Manganese gluconate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5455
Manganese glycerophosphate.
(a) Product. Manganese glycerophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5458
Manganese hypophosphite.
(a) Product. Manganese hypophosphite.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5461
Manganese sulfate.
(a) Product. Manganese sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5464
Manganous oxide.
(a) Product. Manganous oxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5470
Mannitol.
(a) Product. Mannitol.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5475
Methionine.
(a) Product. Methionine.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.
§ 582.5477
Methionine hydroxy analog and its calcium salts.
(a) Product. Methionine hydroxy analog and its calcium salts.
(b) [Reserved]
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.
§ 582.5530
Niacin.
(a) Product. Niacin.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5535
Niacinamide.
(a) Product. Niacinamide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5580
D-Pantothenyl alcohol.
(a) Product. D-Pantothenyl alcohol.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5590
Phenylalanine.
(a) Product. Phenylalanine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5622
Potassium chloride.
(a) Product. Potassium chloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5628
Potassium glycerophosphate.
(a) Product. Potassium glycerophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5634
Potassium iodide.
(a) Product. Potassium iodide.
(b) Tolerance. 0.01 percent.
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in table salt as a source of dietary iodine in accordance with good manufacturing or feeding practice.
§ 582.5650
Proline.
(a) Product. Proline (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5676
Pyridoxine hydrochloride.
(a) Product. Pyridoxine hydrochloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5695
Riboflavin.
(a) Product. Riboflavin.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5697
Riboflavin-5-phosphate.
(a) Product. Riboflavin-5-phosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5701
Serine.
(a) Product. Serine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5772
Sodium pantothenate.
(a) Product. Sodium pantothenate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5778
Sodium phosphate.
(a) Product. Sodium phosphate (mono-, di-, and tribasic).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5835
Sorbitol.
(a) Product. Sorbitol.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5875
Thiamine hydrochloride.
(a) Product. Thiamine hydrochloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5878
Thiamine mononitrate.
(a) Product. Thiamine mononitrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5881
Threonine.
(a) Product. Threonine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5890
Tocopherols.
(a) Product. Tocopherols.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5892
a-Tocopherol acetate.
(a) Product. a-Tocopherol acetate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5915
Tryptophane.
(a) Product. Tryptophane (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5920
Tyrosine.
(a) Product. Tyrosine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5925
Valine.
(a) Product. Valine (L- and DL-forms).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5930
Vitamin A.
(a) Product. Vitamin A.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5933
Vitamin A acetate.
(a) Product. Vitamin A acetate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5936
Vitamin A palmitate.
(a) Product. Vitamin A palmitate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5945
Vitamin B1
2.
(a) Product. Vitamin B1
2.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5950
Vitamin D2.
(a) Product. Vitamin D2.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5953
Vitamin D3.
(a) Product. Vitamin D3.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5985
Zinc chloride.
(a) Product. Zinc chloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5988
Zinc gluconate.
(a) Product. Zinc gluconate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5991
Zinc oxide.
(a) Product. Zinc oxide.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5994
Zinc stearate.
(a) Product. Zinc stearate prepared from stearic acid free from chick-edema factor.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.5997
Zinc sulfate.
(a) Product. Zinc sulfate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
Subpart G—Sequestrants 2
§ 582.6033
Citric acid.
(a) Product. Citric acid.
2 For the purpose of this subpart, no attempt has been made to designate those sequestrants that may also function as chemical preservatives.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6085
Sodium acid phosphate.
(a) Product. Sodium acid phosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6099
Tartaric acid.
(a) Product. Tartaric acid.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6185
Calcium acetate.
(a) Product. Calcium acetate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6193
Calcium chloride.
(a) Product. Calcium chloride.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6195
Calcium citrate.
(a) Product. Calcium citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6197
Calcium diacetate.
(a) Product. Calcium diacetate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6199
Calcium gluconate.
(a) Product. Calcium gluconate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6203
Calcium hexametaphosphate.
(a) Product. Calcium hexametaphosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6215
Monobasic calcium phosphate.
(a) Product. Monobasic calcium phosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6219
Calcium phytate.
(a) Product. Calcium phytate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6285
Dipotassium phosphate.
(a) Product. Dipotassium phosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6290
Disodium phosphate.
(a) Product. Disodium phosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6386
Isopropyl citrate.
(a) Product. Isopropyl citrate.
(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.02 percent in accordance with good manufacturing or feeding practice.
§ 582.6511
Monoisopropyl citrate.
(a) Product. Monoisopropyl citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6625
Potassium citrate.
(a) Product. Potassium citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
[41 FR 38657, Sept. 10, 1976. Redesignated at 42 FR 14091, Mar. 15, 1977]
§ 582.6751
Sodium citrate.
(a) Product. Sodium citrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
[41 FR 38657, Sept. 10, 1976. Redesignated at 42 FR 14091, Mar. 15, 1977]
§ 582.6754
Sodium diacetate.
(a) Product. Sodium diacetate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6757
Sodium gluconate.
(a) Product. Sodium gluconate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6760
Sodium hexametaphosphate.
(a) Product. Sodium hexametaphosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6769
Sodium metaphosphate.
(a) Product. Sodium metaphosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6778
Sodium phosphate.
(a) Product. Sodium phosphate (mono-, di-, and tribasic).
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6787
Sodium pyrophosphate.
(a) Product. Sodium pyrophosphate.
(b) Condition of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6789
Tetra sodium pyrophosphate.
(a) Product. Tetra sodium pyrophosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6801
Sodium tartrate.
(a) Product. Sodium tartrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6804
Sodium potassium tartrate.
(a) Product. Sodium potassium tartrate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6807
Sodium thiosulfate.
(a) Product. Sodium thiosulfate.
(b) Tolerance. 0.1 percent.
(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in salt in accordance with good manufacturing or feeding practice.
§ 582.6810
Sodium tripolyphosphate.
(a) Product. Sodium tripolyphosphate.
(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
§ 582.6851
Stearyl citrate.
(a) Product. Stearyl citrate.
(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.15 percent in accordance with good manufacturing or feeding practice.