[Federal Register Volume 61, Number 26 (Wednesday, February 7, 1996)]
[Notices]
[Pages 4630-4631]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 96-2635]
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DEPARTMENT OF ENERGY
Office of Energy Research
Energy Research Financial Assistance Program Notice 96-08: Human
Genome Program; Technological Advances
AGENCY: U.S. Department of Energy (DOE).
ACTION: Notice inviting grant applications.
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SUMMARY: The Office of Health and Environmental Research (OHER) of the
Office of Energy Research (ER), U.S. Department of Energy, hereby
announces its interest in receiving grant applications in support of
the DOE Human Genome Program (HGP). This program is a coordinated,
multidisciplinary, goal-oriented research effort to obtain a detailed
understanding of the human genome at the molecular level. The objective
of this notice is to promote substantive improvements in high-
throughput, integrated approaches to large-scale human genome
sequencing and its analysis. The solicited topics are: (1) Supportive
instrumentation and automation systems; (2) assembly of multi-megabase
scale, ordered and sequence-ready DNA clones; (3) informatics for the
rapid assembly, analysis, and annotation of data from high-throughput
sequencing; and (4) informatics for facile submission, retrieval, and
visualization of data for single or multiple related databases,
specifically including the Genome Data Base and the Genome Sequence
Data Base. Applicants must address clearly how the proposed work will
help achieve the sequencing goals of the HGP. Collaborative,
multidisciplinary efforts are specifically encouraged.
DATES: Potential applicants are strongly encouraged to submit a brief
preapplication. All preapplications, referencing Program Notice 96-08,
should be received by DOE by 4:30 p.m. E.S.T., March 28, 1996. A
response discussing the potential program relevance of a formal
application generally will be communicated to the applicant within 30
days of receipt. The deadline for receipt of formal applications
submitted in response to this notice must be received by 4:30 p.m.,
E.D.T., July 11, 1996, in order to be accepted for merit review in
September 1996 and to permit timely consideration for awards in fiscal
year 1997.
ADDRESSES: All preapplications, referencing Program Notice 96-08,
should be sent to Ms. Joanne Corcoran, U.S. Department of Energy,
Office of Health and Environmental Research, ER-72, 19901 Germantown
Road, Germantown, MD 20874-1290.
After receiving notification from DOE concerning successful
preapplications, applicants may prepare formal applications and send
them to: U.S. Department of Energy, Office of Energy Research, Grants
and Contracts Division, ER-64, 19901 Germantown Road, Germantown, MD
20874-1290, ATTN: Program Notice 96-08. The above address for formal
applications also must be used when submitting formal applications by
U.S. Postal Service Express Mail, any commercial mail delivery service,
or when handcarried by the applicant.
FOR FURTHER INFORMATION CONTACT: Dr. Gerald Goldstein, if referencing
topic (1); Dr. Marvin Stodolsky, if referencing topic (2); and Dr. Jay
Snoddy, if referencing topics (3) or (4) at the U.S. Department of
Energy, Office of Health and Environmental Research, ER-72, 19901
Germantown Road, Germantown, MD 20874-1290, by telephone (301) 903-
6488, by facsimile (301) 903-8521, or preferably by E-mail,
[email protected]. General HGP information can also be
obtained on the World Wide Web (WWW) Internet browsers at: http://
www.er.doe.gov/production/oher/hug____top.html, http://www.ornl.gov/
techresources/human____genome/home.html, and sites linked to these WWW
pages. The 5-year goals of the U.S. HGP are published in the journal,
Science, volume 262, pages 43-46.
SUPPLEMENTARY INFORMATION: The brief preapplication, in accordance with
10 CFR 600.10(d)(2), should consist of two to three pages of narrative
describing the research objectives and methods of accomplishment. The
preapplications will be reviewed for relevance to the notice, and
further instructions will be provided with the response.
Preapplications determined by staff of the Office of Health and
Environmental Research to be insufficiently directed at the goals of
this notice will be returned without further review to the applicant.
Telephone and FAX numbers are required parts of the preapplication, and
electronic mail addresses are desirable.
It is anticipated that approximately $2,000,000 will be available
for grant awards in this area during FY 1997, contingent upon
availability of appropriated funds. Multiple year funding of grant
awards is expected, and is also contingent upon availability of funds,
progress of the research, and continuing program need. Projected awards
will be in the range of $50,000 per year up to $1,000,000 per year with
terms of 2 to 3 years.
Information on the development and submission of applications,
eligibility, limitations, evaluation, selection process, and other
policies and procedures may be found in 10 CFR Part 605, and in the
Application Guide for the Office of Energy Research Financial
Assistance Program. The Application Guide is available from the U.S.
Department of Energy, Office of Health and Environmental Research,
Health Effects and Life Sciences Research Division, ER-72, 19901
Germantown Road, Germantown, MD 20874-1290. Telephone requests may be
made by calling (301) 903-6488. Internet requests can be made to:
[email protected]. Electronic access to ER's Financial
Assistance Guide is possible via the Internet using the following E-
mail address: http://www.er.doe.gov
The Office of Energy Research, as part of its grant regulations,
requires at 10 CFR 605.11(b) that a grantee funded by ER and performing
research involving recombinant DNA molecules and/or organisms and
viruses containing recombinant DNA molecules shall comply with the
National Institutes of Health ``Guidelines for Research Involving
Recombinant DNA Molecules'' (59 FR 34496, July 5, 1994) or such later
revision of those guidelines as may be published in the Federal
Register.
The Catalog of Federal Domestic Assistance Number for this program
is 81.049, and the solicitation control number is ERFAP 10 CFR part
605.
Issued in Washington, DC, on January 24, 1996.
John Rodney Clark,
Associate Director for Resource Management, Office of Energy Research.
[FR Doc. 96-2635 Filed 2-6-96; 8:45 am]
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