[Federal Register Volume 64, Number 98 (Friday, May 21, 1999)]
[Notices]
[Page 27797]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 99-12835]


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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention


Availability of Draft Guidelines for Prevention of Opportunistic 
Infections in Persons Infected With Human Immunodeficiency Virus

AGENCY: Centers for Disease Control and Prevention (CDC), Department of 
Health and Human Services.

ACTION: Notice of availability and request for comments.

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SUMMARY: This notice announces the availability of a draft document 
entitled ``1999 USPHS/IDSA Guidelines for the Prevention of 
Opportunistic Infections in Persons Infected with Human 
Immunodeficiency Virus,'' prepared by representatives of the U.S. 
Public Health Service (USPHS), the Infectious Diseases Society of 
America (IDSA), and additional representatives of Federal agencies, 
universities, professional societies, and community organizations, for 
review and comment.

DATES: To ensure consideration, written comments on this draft document 
must be received on or before June 1, 1999.

ADDRESSES: The draft document is available on the World-Wide Web site 
of the AIDS Treatment and Information Service (http://www.hivatis.org). 
Requests for hardcopies of the document may be submitted to the 
Division of HIV/AIDS Prevention, Mailstop E-49, Centers for Disease 
Control and Prevention, Atlanta, GA 30333; telephone (404) 639-2072, 
FAX (404) 639-2007. Written comments on this draft document should be 
sent to the above address for receipt by June 1, 1999.

FOR FURTHER INFORMATION CONTACT: Division of HIV/AIDS Prevention, 
National Center for HIV, STD, and TB Prevention, Mailstop E-49, Centers 
for Disease Control and Prevention, Atlanta, GA 30333; telephone (404) 
639-2072, FAX (404) 639-2007.

SUPPLEMENTARY INFORMATION: Opportunistic infections constitute a major 
cause of morbidity and mortality in persons infected with human 
immunodeficiency virus. The draft 1999 Guidelines, prepared by the 
United States Public Health Services, the Infectious Diseases Society 
of America, and representatives of Federal agencies, universities, 
professional societies, and community organizations, represent an 
update of guidelines published in 1995 and in 1997. They include 
recommendations to prevent major parasitic, bacterial, mycotic, and 
viral infections in the era of highly active antiretroviral therapy 
(HAART). They address prevention of disease by chemoprophylaxis and 
vaccination and prevention of exposure to opportunistic pathogens. They 
also address discontinuing chemoprophylaxis against specific pathogens 
when the CD4+ lymphocyte count has increased in response to HAART.

    Dated: May 17, 1999.
Joseph R. Carter,
Associated Director for Management and Operations, Centers for Disease 
Control and Prevention (CDC).
[FR Doc. 99-12835 Filed 5-20-99; 8:45 am]
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